1). To study the model for establishments the prevention and control S. stercoralis parasites strategy in people, animals and environment in village in endemic area. 2). To study the setting of holistic management for prototype village with the sustainable of S. stercoralis free populations. 3). To study the new knowledge with focus on strongyliodiasis i.e. biology, epidemiology, clinical sign and symptoms, diagnosis and treatment in Thailand and nearby countries.
โครงการย่อยที่ 2
1). To develop new detection tools, real-time PCR, droplet digital PCR and pyrosequencing methods for detection of tropical neglected parasites as well as serological tests for diagnosis of neglected parasitosis. 2). To study the clinical features and epidemiological characteristics of tropical neglected parasites in Greater Mekong subregion. 3). To study effect of anti parasitic drugs for treatment of tropical neglected parasites.
โครงการย่อยที่ 3
1). To study molecular evidence and differentiation and detection of tropical neglected parasites from various regions of Thailand, Myanmar and Lao PDR. 2).To analyze the sequence data of these parasites and create a phylogenetic tree in order to demonstrate the relationship of each genus of these parasites in Thailand, Myanmar and Lao PDR with other species of the parasites in each genus from different countries, which have been reported in GenBank.
โครงการย่อยที่ 4
1). To prepare mosquito repellent formulations of Ligusticum sinense hexane extract (LHE). 2).To investigate under laboratory conditions the repellent activity of the formulated preparations against Ae. aegypti. The best repellent formulations will be candidates for developing effective repellent products by a novel technology. 3).To evaluate under laboratory conditions the repellent activity of products developed against various mosquito vectors such as Ae. aegypti and/or Anopheles minimus, etc. 4). To determine under laboratory conditions the physical and biological stability of plant-based repellents. 5). To investigate under field conditions the repellent activity of plant-based repellents against a natural population of mosquitoes. 6). To determine under laboratory and field conditions the potential skin irritant and satisfaction of human volunteers when applying plant-based repellents.
